Facial Swelling Causes - 11 Reasons For A Puffy, Swollen Face - Facial puffiness causes Like 68.54% | 439 votes Views: 554 366 Download Allergic reaction. eye infection, such as allergic conjunctivitis. Categories: Spider Comments: Add Comment Cancel By Tazil - 12:31 Side effect of medication. By Mojin - 04:49 Cellulitis, a bacterial infection of the skin. By Akit - 18:53 Hormonal disturbance, such as thyroid diseases. By Gall - 22:28 Ladoga-region.info › health › facial-swelling. By Brasho - 04:37 Facial swelling has a range of possible causes, from minor events like sleeping on your face to serious medical conditions like anaphylaxis.